Proyectos y Publicaciones

• Canseco J.A., Niklitschek E.J., Harrod C. (2021) Variability in C and N trophic discrimination factors for teleost fishes: a meta-analysis of temperature and dietary effects. Reviews in Fish Biology and Fisheries DOI: 10.1007/s11160-021-09689-1

• Sánchez-Hernández, J., Hayden, B., Harrod, C. & Kahilainen, K.K. (2021) Population niche breadth and individual trophic specialisation of fish along a climate-productivity gradient. Reviews in Fish Biology and Fisheries 31, 1025-1043

• Santana-Sagredo, F., Schulting, R.J., Méndez-Quiros, P., Vidal-Elgueta, A., Uribe, M., Loyola, R., Maturana-Fernández, A., Díaz, F.P., Latorre, C., McRostie, V.B., Santoro, C.M., Mandakovic, V., Harrod, C. & Lee-Thorp, J. (2021) ‘White Gold’ guano fertiliser drove agricultural intensification in the Atacama Desert from 1000AD. Nature Plants 7, 152-158

• Bon, M., Grall, J., Gusmao, J.B., Fajardo, M., Harrod, C., & Pacheco, A.S. (2021) Functional changes in benthic macrofaunal communities along a natural gradient of hypoxia in an upwelling system. Marine Pollution Bulletin. 164, 112056

• Zapata-Hernández, G., Sellanes, J., Letourneur, Y., Harrod, C., Morales, N., Plaza, P., Meerhof, E., Yannicelli, B., Carrasco, S.A., Hinojosa, I., & Gaymer, C. (2021) Tracing organic matter sources through the marine ecosystem of Rapa Nui (Easter Island). Aquatic Conservation: Marine and Freshwater Ecosystems 31, 304-323

• Saccò, M., White, N.E., Harrod, C., Salazar, G., Aguilar, P., Cubillos, C.F., Meredith, K., Baxter, B.K., Oren, A., Anufriieva, E., Shadrin, N., Marambio-Alfaro, Y., Bravo-Naranjo, V. and Allentoft, M.E. (2021), Salt to conserve: a review on the ecology and preservation of hypersaline ecosystems. Biological reviews, 96: 2828-2850. https://doi.org/10.1111/brv.12780

• Zapata-Carmona H, Barón L, Kong M, Morales P. (2021). Protein Kinase A (PRKA) Activity Is Regulated by the Proteasome at the Onset of Human Sperm Capacitation.  10(12):3501. doi:10.3390/cells10123501.

• Zuñiga LM, Andrade JC, Fábrega-Gueren, Orihuela P, Velásquez E, Vidal E, Gutiérrez R, Morales P, Gómez-Silva B, Croxatto H. (2021). Mating induces early transcriptional response in the rat endosalpinx: the role of TNF and RA. 161(1):43-59. doi: 10.1530/REP-20-0190.

• Villalobos, A., Wiese, J., Borchert, W., Rahn, T., Slaby, B., Steiner, L., Künzel, S., Dorador, C., and Imhoff, J. (2021) Micromonospora tarapacensis sp. nov., a bacterium isolated from a hypersaline lake. International Journal of Systematic and Evolutionary microbiology, 71(11). https://doi.org/10.1099/ijsem.0.005109

• Bonelli, C. and Dorador, C. (2021) Endangered Salares: microdisasters in Northern Chile, Tapuya: Latin American Science, Technology and Society, 4(1),1968634.

• Molina, V., Eissler, Y., Fernandez, C., Cornejo-D’Ottone, M., Dorador, C., Bebout, B., Jeffrey, W., Romero C., and Hengst, M. (2021). Greenhouse gases and biogeochemical diel fluctuations in a high-altitude wetland. Science of The Total Environment, 768, 144370. 

• Ana Zárate, Cristina Dorador , Jorge Valdés , Verónica Molina , Gonzalo Icaza , Aldo S Pacheco , Alexis Castillo .(2021). Benthic Microbial Diversity Trends In Response To Heavy Metals In An Oxygen Deficient Eutrophic Bay Of The Humboldt Current System Offshore The Atacama Desert. Environmental Pollution. DOI: 1016/J.ENVPOL.2021.117281.

• Ortiz M & R Uribe (2021). Comparing the stability of successional models in kelp forest and barrens (SE Pacific): implications for conservation monitoring. Aquatic Conservation: Marine Freshwater Ecosystem. DOI: doi.org/10.1002/aqc.3497.

• Javier Palacios, Julio Benites , Gareth I Owen , Pablo Morales , Mario Chiong , Chukwuemeka R Nwokocha , Adrián Paredes , Fredi Cifuentes  (2021) Impact of the Potential Antitumor Agent 2-(4-Hydroxyphenyl) Amino-1,4-Naphthoquinone (Q7) on Vasomotion Is Mediated by the Vascular Endothelium, But Not Vascular Smooth Muscle Cell Metabolism J Cardiovasc Pharmacol. doi: 10.1097/FJC.0000000000000940.

• Fernando Ayavire , José Miguel Fonseca , Felipe Salas , Julio Benites , Chukwuemeka R. Nwokocha , Adrián Paredes , Fredi Cifuentes & Javier Palacios. (2021) Ascorbic supplementation attenuates juglone induced metabolic derangement. BOLETIN LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROMÁTICAS. org/10.37360/blacpma.21.20.2.15

• Sofía Sanhueza, Nicolás Tobar, Mariana Cifuente, Daniela Quenti, Rosaria Varì,  Beatrice Scazzocchio,  Roberta Masella,  Karin Herrera, Adrián Paredes,  Glauco Morales, Paulina Ormazabal. (2021). Lampaya Medicinalis Phil. decreases lipid-induced triglyceride accumulation and proinflammatory markers in human hepatocytes and fat body of Drosophila melanogaster. Physiology and Biochemistry. org/10.1038/s41366-021-00811-8.

• Juan Güiza, Aníbal García , Javiera Arriagada^,  Camila Gutiérrez , Jorge González , Valeria Márquez-Miranda , Melissa Alegría-Arcos , Yorley Duarte , Maximiliano Rojas , Fernando González-Nilo , Juan C Sáez , José L Vega. (2021). Unnexins: Homologs of innexin proteins in Trypanosomatidae parasites. J Cell Physiol. doi: 10.1002/jcp.30626.

• Ximena López, Nicolás Palacios-Prado, Juan Güiza, Rosalba Escamilla, Paola Fernández, José L. Vega, Maximiliano Rojas, Valeria Marquez-Miranda, Eduardo Chamorro, Ana M. Cárdenas, María Constanza Maldifassi, Agustín D. Martínez, Yorley Duarte, Fernando D. González-Nilo, and Juan C. Sáez. (2021). A physiologic rise in cytoplasmic calcium ion signal increases pannexin1 channel activity via a C-terminus phosphorylation by CaMKII. doi.org/10.1073/pnas.2108967118.

• Juan Güiza , Javiera Arriagada, Luis Rodríguez ¹, Camila Gutiérrez , Yorley Duarte , Juan C Sáez , José L Vega. (2021). Anti-parasitic drugs modulate the non-selective channels formed by connexins or pannexins. Biochim Biophys Acta Mol Basis Dis. doi: 10.1016/j.bbadis.2021.166188.

• Dirk Schulze-Makuch, Daniel Lipus , Felix L. Arens , Mickael Baqué , Till L. V. Bornemann , Jean-Pierre deVera , Markus Flury , Jan Frösler , Jacob Heinz , Yunha Hwang , Samuel P. Kounaves, Kai Mangelsdorf, Rainer U. Meckenstock, Mark Pannekens , Alexander J. Probst , Johan S. Sáenz, Janosch Schirmack , Michael Schloter, Philippe Schmitt-Kopplin, Beate Schneider , Jenny Uhl , Gisle Vestergaard, Bernardita Valenzuela, Pedro Zamorano and Dirk Wagner (2021). Microbial Hotspots in Lithic Microhabitats Inferred from DNA Fractionation and Metagenomics in the Atacama Desert. Microorganisms. doi.org/10.3390/microorganisms9051038.

• Santos, Andres; Bruna, Pablo; Martinez-Urtaza, Jaime; Solis, Francisco; Valenzuela, Bernardita; Zamorano, Pedro; Barrientos, Leticia. (2021). Two Archaeal Metagenome-Assembled Genomes from El Tatio Provide New Insights into the Crenarchaeota Phylum. Doi: 10.3390/genes12030391.

• Melo F, Caballero L, Zamorano E, Ventura N, Navarro C, Doll I, Zamorano P, Cornejo A. (2021.) The cytotoxic effect of α-synuclein aggregates. DOI: 10.1002/cphc.202000831.

• Zarate R, Arancibia D, Fernandez A, Signorelli J, Larrondo L, André E, Zamorano P. (2021). Optimization of the Light-On system in a lentiviral platform to a light-controlled expression of genes in neurons. Electronic Journal of Biotechnology. DOI 10.1016/j.ejbt.2021.03.006

Libros

• Hermosillo-Núñez B, Ortiz M, Jordán F (2021) Keystone species complexes and macroscopic properties for improving ecosystem-based conservation practices in kelp forest along the north-central Chilean coast. In: Ortiz M & F Jordán (Eds). Marine coastal ecosystem modelling and conservation: Latin American experiences. Springer, Switzerland, pp. 95-126.

• González J, Ortiz M (2021) Exploring alternative management policies for benthic ecological systems of northern Chile (SE Pacific). In: Ortiz M & F Jordán (Eds.). Marine coastal ecosystem modelling and conservation: Latin American experiences. Springer, Switzerland, pp. 127-142.

• Rodríguez-Zaragoza F, Ortiz M (2021) Dynamic and spatial models for the coral reef of Banco Chinchorro Biosphere Reserve (Caribbean Sea) for assessment harvest scenarios: short-term responses. In: Ortiz M & F Jordán (Eds.). Marine coastal ecosystem modelling and conservation: Latin American experiences. Springer, Switzerland, pp. 163-178.

• Ortiz M, F Jordán (2021) Modelling aim the conservation of coastal marine ecosystem in Latin America. In: Ortiz M & F Jordán (Eds.). Marine coastal ecosystem modelling and conservation: Latin American experiences. Springer, Switzerland, pp. 203-207.
• Harrod, C. & Stallings, C.D. (2021). Trophodynamics. In Methods in Fish Biology Ed. II (Eds S. Midway, C. Hasler, and P. Chakrabarty). American Fisheries Society, USA.

• González J, Ortiz M (2021) Exploring alternative management policies for benthic ecological systems of northern Chile (SE Pacific). In: Ortiz M & F Jordán (Eds.). Marine coastal ecosystem modelling and conservation: Latin American experiences. Springer, Switzerland, pp. 127-142.

• Rodríguez-Zaragoza F, Ortiz M (2021) Dynamic and spatial models for the coral reef of Banco Chinchorro Biosphere Reserve (Caribbean Sea) for assessment harvest scenarios: short-term responses. In: Ortiz M & F Jordán (Eds.). Marine coastal ecosystem modelling and conservation: Latin American experiences. Springer, Switzerland, pp. 163-178.

Actividades No Logradas o Pendientes del Instituto Antofagasta:

• Phytochemical study and antioxidant activity of an endemic plant of the high-planes of Northern Chile Werneria glaberrima: Protective effect in cellular models of Parkinson’s disease. FONDECYT Iniciación Nº11190972 (2019 – 2022). Dr. Adrian Paredes.

• Hypotensive and antihypertensive effects of pure compounds isolated from Senecio nutans (Sch.) Bip. and Xenophylum poposum (Phil.) V.A. Funk on cardiovascular system by calcium dependent and independent mechanisms. FONDECYT Regular Nº1200610 (2020-2023). Dr. Adrian Paredes (Co-I), Fredi Cifuentes (Co-I).

• Molecular bricks for thermoenzymes expression. VIU20P0029 MB Thermosystems: VIU-FONDEF-ANID (2021-2022) . Dr. Pedro Zamorano M.

• “Ingeniería metabólica a través de biología sintética de una bacteria etanologénica termófila, Geobacillussp. cepa C3: Optimización para la producción de bioetanol” Semillero de Investigación UA (2019-2022). Dr. Pedro Zamorano M.

• Feeding rivers and lakes: source and fate of land based salmon aquaculture waste water in Southern Chile (Lake Villarrica watershed). Fondecyt Regular 1200205 (2020-2023) Chris Harrod (Co-I).

• Using stable isotope values of pre-historical (shell midden) and contemporary marine consumers to characterise change and the relaPve role of natural and anthropogenic disturbance in coastal food webs over 13 000 years. Fondecyt Regular 1191452. (2019-2023) . Chris Harrod (PI), Pablo Pérez, (Co-I).

• From the Holocene to the Anthropocene: ReconstrucPng shiVing paleoecological baselines using shell middens from northern Chile. Fondecyt Regular 1191568 (2019-2023) Chris Harrod (Co-I)

• Estrategias de explotación de camélidos y cambio climáPco en la Puna de Atacama durante el Holoceno tardío: el aporte del análisis isotópico secuencial. Fondecyt Postdoc 3190566 (2019-2022) Chris Harrod (Sponsor), Celeste Samec (PI).

• Caracterización de los roles de absorción química versus ingesta biológica de metales pesados en especies de una cuenca de un río altamente contaminado. Fondecyt Postdoc 3190786 (2019-2022) Chris Harrod (Sponsor), Pablo Pérez (PI).

• Centro de Biotecnología y Bioingeniería (CeBIB) 3765. Proyecto Basal (2019-2024).  Cristina Dorador (PI)

• MMEX: Phylogenetic novelty and symbiotic interactions in microbial mats from extreme environments. Proyecto ECOS-SUD (2020-2022) Cristina Dorador (PI), Pablo Aguilar (Co-I) 

• Functional ecology of Chilean precordillera lakes: towards a Wetland Health Index for birds. Proyecto eDGES Programme (BHP-Curtin alliance) (2020-2025) Pablo Aguilar (Investigador adjunto)

• Núcleo Milenio de Salmónidos Invasores (INVASAL). Iniciativa Científica Milenio. (2021-2024) Pablo Aguilar (Investigador adjunto).

• Estudiar el proceso de ubiquitinación de proteínas y la participación de algunas de las enzimas de esta vía en la capacitación de espermatozoides humanos. Proyecto puente de investigación en excelencia. (2018-2022) Patricio Morales.

Proyectos 2022 del Instituto:

• “Rhizosphere Extreme Microbiome Consortium (REMC): a national network for a multiomic-based approach for a rational design, build and prospection of microbial consortia from extreme environment plants to mitigate the megadrought in Chile”, Fondos Sequía 2022. ANID. Pedro Zamorano M.

• Isolation and bioactivity of phenolics from native small fruits from Chile: Countercurrent chromatography and bioprospection of neglected berries using conventional and green methodologies and potential use on the prevention of chronic disease. Fondecyt Regular 1220075  (2022-2025). Fredi Cifuentes (Co-I)